1 2 4 trichlorobenzene structure

Some of the following links exit EPA's site Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. Petit, J.C.; TerMinassian, L., Sears, G.W. Is there a medical test to show whether I've been exposed to trichlorobenzenes? Synonyms. Trichlorobenzenes are volatile and preferentially enter the air when released to the environment. You will be subject to the destination website's privacy policy when you follow the link. 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Transl. Biochem. Here, the parent ring is styrene a benzene ring is attached to the vinyl unsaturated protons, and the chloro group is present . following TRC products: Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. HeH + has bond order 1.. for GPC of polyolefines such as PE or PP which are otherwise insoluble. J. Chem. The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, [all data], Spieksma, Luijk, et al., 1994 L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. Thermodynam., 1982, 14, 303-308. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. 1,2,4-Trichlorobenzene. 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. Eng. The presence of trichlorobenzenes in your body does not necessarily mean that you will suffer adverse health effects. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. - 298. A dermal exposure study in mice was found inadequate for drawing conclusions as to carcinogenicity in humans. Chem. Huaxue Xuebao, 1987, 45, 1184. MSDS/SDS Database Search | A method for forming a multilayer meltblown composite, consisting of: meltblowing a first material to form a first meltblown layer, wherein the first material comprises one or more resins having an Ultimate Elongation (UE) of from about 50% to about 250%; meltblowing a second material to form a second meltblown layer, wherein the second material comprises one or more . Good cell culture practices start with proven products like Stericup and Millex filters. BS - Robert L. Brown and Stephen E. Stein In addition to the Thermodynamics Research Center Catalog number: 157900025. P264: Wash skin thoroughly after handling. HeH + contains all paired electrons. Jondorf, W.R.; Williams, R.T., J. Chem. Notice: This spectrum may be better viewed with a Javascript [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. with the development of data collections included in The . Yan, H.; Gu, J.; An, X.; Hu, R., There are no studies of cancer in people exposed to trichlorobenzenes. endstream endobj 26 0 obj <>stream Together. Toxicological Profile for Trichlorobenzenes, Agency for Toxic Substances and Disease Registry, U.S. Department of Health & Human Services. Future versions of this site may rely on been selected on the basis of sound scientific judgment. Data compilation copyright CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). The lower energy states of HeH + is reached when product formed are He + H +.. 1,2,4-Trichlorobenzene is produced in large Note: Please consider using the ; Nibbering, N.M.M., (Engl. 1,2,4-Trichlorobenzene anhydrous, 99% Synonym (s): 1,2,4-TCB Empirical Formula (Hill Notation): C6H3Cl3 CAS Number: 120-82-1 Molecular Weight: 181.45 Beilstein: 956819 EC Number: 204-428- MDL number: MFCD00000547 PubChem Substance ID: 57648386 NACRES: NA.21 Pricing and availability is not currently available. Moreover, the free concentration Get all suppliers and price by the below link: Home | Russ. Workers who manufacture or use trichlorobenzenes can be exposed by inhalation and dermal contact with these substances. J. Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Primary and secondary antibodies, blockers and custom services. [all data], Weast and Grasselli, 1989 *Disclaimer: The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. Standard Reference Data Act. J. Phys. 10. United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. You can review and change the way we collect information below. Chem. that these items are necessarily the best available for the purpose. Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. This fact sheet is one in a series of summaries about hazardous substances and their health effects. Agency for Toxic Substances and Disease Registry [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. To view more metadata about the specific Synonym, click on the Synonym. [all data], Stull, 1947 Create the perfect solution - match and clear hexagones. Ind. NIST subscription sites provide data under the Please see the following for information about All information these cookies collect is aggregated and therefore anonymous. 1,2,4-Trifluorobenzene | C6H3F3 - PubChem compound Summary 1,2,4-Trifluorobenzene Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Safety and Hazards 8 Literature 9 Patents 10 Classification 11 Information Sources 1 Structures CAS 120-82-1, chemical formula CH-1,2,4-(Cl). P264: Wash skin thoroughly after handling. Compound E is 4-Bromo 1-chloro 2-methyl benzene. 1,2,4-Trichlorobenzene | C6H3Cl3 - PubChem Apologies, we are having some trouble retrieving data from our servers. Measurements of Saturated Vapor Pressure above the Liquid Phase for Isomeric Dichlorobenzenes and 1,2,4-Trichlorobenzene, 1000. Properties Grade anhydrous Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 H410: Very toxic to aquatic life with long lasting effects. : Washington, D. C., 1955. The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Journal of Chromatography A, 1994, 672, 1-2, 141-148, https://doi.org/10.1016/0021-9673(94)80602-0 the on behalf of the United States of America. Chemsrc provides 1,2,4-Trichlorobenzene(CAS#:120-82-1) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. Combustible. This Website requires your browser to be JavaScript enabled. Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. III. Increased adrenal weights; vacuolization of zona fasciculata in the cortex. displays seen below. HU0~]$'RWS`HlE*'G8 . In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Trichlorobenzenes can be measured in blood and body fat, but the tests used are not routinely available in the doctor's office. Imaging flow cytometry makes it possible. If required, we will contact you for this information once your order is placed. We take your privacy seriously. J. Chem. Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 118 K) (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. Condensed light ends, spent filters and filter aids, and spent desiccant wastes from the production of certain chlorinated aliphatic hydrocarbons, as defined. d(ln(kH))/d(1/T) = Temperature dependence constant (K), Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: How can trichlorobenzenes affect my health? An invalid quantity was specified. [all data], Galat, 1952 From: Modern Inorganic Synthetic Chemistry, 2011 Related terms: Aqueous Solution View all Topics Download as PDF About this page Trichlorobenzenes Spieksma, Walter; Luijk, Ronald; Govers, Harrie A.J., P = vapor pressure (bar) J., 1958, 69, 181. Dreisbach, R.R., Converge, Intensify and Evolve. It is a derivative of benzene with three chloride substituents. LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. Formula. Data compiled by: Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, Go To: Top, Gas phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Molecular Weight 181.45. The purpose of the fee is to recover costs associated 9-9BNKN!%Si)gNAGj!{pp{Pa9#b0RFH1r8(Byy4(L4iPhAAOJ= * T~_O)~?/S~_oF\B[Nn{(}fPyqMKo D4' Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, NIST Standard Reference Select a region with data to zoom. NOAA: CAMEO Chemicals - It is a colorless liquid used as a solvent for a variety of compounds and materials. Synthesis Reference(s): Journal of the American Chemical Society, 74, p. 3890, 1952 DOI: 10.1021/ja01135a052: Physical Properties for CAS 120-82-1: Anion assigned based on ab initio calculations. These clinics specialize in recognizing, evaluating, and treating illnesses resulting from exposure to hazardous substances. Chem., 1947, 39, 4, 517-540, https://doi.org/10.1021/ie50448a022 Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 Cosolvents are often needed to dissolve these chemicals in cell culture medium. Explore, interact. click the mouse on the plot to revert to the orginal display. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., [all data], Petit and TerMinassian, 1974 Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), All references to Merck refer to Merck KGaA, Darmstadt, Germany. shall not be liable for any damage that may result from Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. the library and of all reactions involving this species. Acta, 1986, 105, 101-110. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. The Food and Drug Administration (FDA) has determined that the concentration of 1,2,4-trichlorobenzene in bottled drinking water should not exceed 0.07 mg/L. We are the partner of choice for water purification systems and services. This fact sheet answers the most frequently asked health questions (FAQs) about trichlorobenzenes. All rights reserved. intended to imply recommendation or endorsement by the National Optimize your QC lab workflow and ensure regulatory compliance. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. uses its best efforts to deliver a high quality copy of the Toggle navigation. The product quantity has been adjusted. 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. H410: Very toxic to aquatic life with long lasting effects. Toxicol. Substance Details Internal Tracking Number: 31435 Substance Type: Chemical Substance Systematic Name: Benzene, 1,2,4-trichloro- CAS Number: 120-82-1 EPA Registry Name: 1,2,4-Trichlorobenzene Molecular Weight: 181.45 Molecular Formula: C6H3Cl3 Additional Metadata Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file by the U.S. Secretary of Commerce on behalf of the U.S.A. SRD 103b Thermo Data Engine (TDE) for pure compounds, Development of a partition-controlled dosing system for cell assays. Depending on the conditions and additives (e.g., sulfur), it can be the main product from the chlorination of benzene. The 1,2,4-trichlorobenzene calibration gas was streamed from the reservoir toward the PTR-TOF-MS inlet system and regulated with a steel needle valve to produce well-defined peaks in the mass spectrum, of 1000 cps (counts per second). All Rights Reserved. Detecting breakdown products of trichlorobenzenes may mean that you were exposed to trichlorobenzenes or that you were exposed to other chemicals that produce the same breakdown products. uses its best efforts to deliver a high quality copy of the Determination of the standard enthalpies of formation of polychlorobenzenes. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. Eur. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Disclaimer, Copyright 2023 ChemSrc All Rights Reserved. 2. Contact Us to ask a question, provide feedback, or report a problem. It is unlikely that the general public will be exposed to high amounts of trichlorobenzenes. Selling Leads | [all data], Jondorf and Williams, 1958 [all data], Ruscic, Klasinc, et al., 1981 For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. Catalogs and product finders. Chim. AC - William E. Acree, Jr., James S. Chickos Promotional price valid on web orders only. The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. Thermochim. Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. Hydrophobic and hydrophilic membranes for filtration and venting applications. NOAEL : 1.48 x 10 1. mg/kg-day. The following list includes links related to the selected substance. J., 2001, 7, 16, 3511-3516, https://doi.org/10.1002/1521-3765(20010817)7:16<3511::AID-CHEM3511>3.0.CO;2-U The effects of exposure to any hazardous substance depend on the dose, the duration, how you are exposed, personal traits and habits, and whether other chemicals are present. Browse 1,2,4-Trichlorobenzene and related products . How might I be exposed to trichlorobenzenes? Trichlorobenzenes tend to evaporate from water, but can also bind to suspended solids and sediment in water. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . Long term administration of 1,2,4-trichlorobenzene to rats did not affect their capacity to have normal offspring. It is a derivative of benzene, consisting of two adjacent chlorine atoms.. Agency for Toxic Substance and Disease Registration. 1 x 10 -2. 2,3,5-Trichlorobenzene-1,4-diol | C6H3Cl3O2 - PubChem compound Summary 2,3,5-Trichlorobenzene-1,4-diol Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Pharmacology and Biochemistry 8 Literature 9 Patents 10 Taxonomy 11 Classification Physical description. 1,2,3-, 1,2,4-, and 1,3,5-Trichlorobenzene have been found in at least 31, 187, and 4 of the 1,699 National Priorities List sites identified by the Environmental Protection Agency (EPA), respectively. Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . [all data], Rohc, Ruzicka, et al., 1998 CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. Synonyms. (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). The LD50 (oral, rats) is 756mg/kg. Some documentation and label information may refer to the legacy brand. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. . Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources 1,2,3-Trichlorobenzene and 1,3,5 trichlorobenzene are produced in lower quantities and have fewer uses. jcamp-plot.js. HTML 5 canvas support. 1,2,4-Trichlorobenzene for synthesis. 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. Chem., 1981, 85, 1490. The isomers may also have different chemical and . On this Wikipedia the language links are at the top of the page across from the article title. The quantity field is empty. Your contract pricing may differ. Copyright for NIST Standard Reference Data is governed by Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References, Notes, Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, Notes, Yan, Gu, et al., 1987 [all data], Sears and Hopke, 1949 Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. 2021 by the U.S. Secretary of Commerce If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Watch, learn and engage with us. H However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. It is also frequently used to produce dyes and textiles. Res. Email: Contact CDC-INFO. . Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. ; Coefficents calculated by NIST from author's data. Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Yan, H.; Gu, J.; An, X.; Hu, R.-H., gas phase; Acid: 1,2,4-trichlorobenzene. The reaction is as follows: HeH + He + H +. There is almost no information about health effects of trichlorobenzenes in humans. Sublimation Pressure Data for Organic Compounds., We are rebranding all of our life science products, labels, packages and documents. [ 1] Application 1,2,4-Trichlorobenzene may be used as a solvent to prepare: dimethylketene -lactone dimer from tetramethyl-1,3-cyclobutanedione [ 2] A new class of spectrophotometers for water analysis. There is virtually no information regarding health effects of trichlorobenzenes in humans. This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . Pioneering excellence with Steritest Symbio Pumps. See EPAs PDF page to learn more. Select a region with no data or Database and to verify that the data contained therein have (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition Organic residuals, excluding spent carbon adsorbent, from the spent chlorine gas and hydrochloric acid recovery processes associated with the production of alpha- (or methyl-) chlorinated toluenes, ring-chlorinated toluenes, benzoyl chlorides, and compounds with mixtures of these functional groups. unsym-trichlorobenzene; 1,2,4-trichlorobenzol. Recommended vapour and sublimation pressures and related thermal data for chlorobenzenes, Use or mention of technologies or programs in this web site is not Synonyms: 1,2,4-Trichlorobenzene. NIST Standard Reference 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. United States Environmental Protection Agency. https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. The following components were used in generating the plot: Additonal code used was developed at NIST: [all data], Jones, 1960 C6H3-1,2,4-(Cl)3. . It is a colorless liquid used as a solvent for a variety of compounds and materials. 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. Fast, safe transfer of plates to isolator. 120-82-1. jcamp-dx.js and Avoiding high consumption of root crops and fish living in trichlorobenzene-contaminated environments will reduce the risk of exposure. other in their chemical structure. Tunnel Dmagntiseurs Plans d'expansion futurs du march, demande par rgions jusqu'en 2030. 2021 by the U.S. Secretary of Commerce The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. the 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. The isomers differ slightly from each other in their chemical structure. This substance exists as a Related Substance of the following substances. All rights reserved. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4 trichlorobenzene is a colorless liquid. Eng. Please enable JavaScript and reload this page. CHEMICAL NAME : Benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER : 120-82-1 BEILSTEIN REFERENCE NO. [all data], Schlosser, Marzi, et al., 2001 Total Toxic Organics (TTO) Effluent Guidelines Part 413.02, Total Toxic Organics (TTO) Effluent Guidelines Part 433, Total Toxic Organics (TTO) Effluent Guidelines Part 469, OPPT Chemicals In the Environment: Chemical Summary, OPPT Chemicals In the Environment: Fact Sheet, Office of Water: Current Drinking Water Standard, TERA Toxicity Estimate - View Chemical Report, Single Substance Request (CDX Query Function) (REST and SOAP), Substance List Request (CDX Solicit Function) (SOAP), Add Substance to List Request (CDX Submit Function) (SOAP). The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. This may be a synopsis of the full weight-of-evidence narrative. Recl. Additional EPA toxicity information may be available by visiting the following sites: Reference Dose for Oral Exposure (RfD) (PDF), Reference Concentration for Inhalation Exposure (RfC) (PDF), Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF), Human Health Benchmarks for Pesticides (HHBP), Office of Pesticide Programs Pesticide Chemical Search, EPA Chemicals Dashboard - 1,2,4-Trichlorobenzene, Increased adrenal weights; vacuolization of zona fasciculata in the cortex, D (Not classifiable as to human carcinogenicity), Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986). such sites. on behalf of the United States of America. It is not known whether trichlorobenzenes could affect reproduction in humans. Data Program, but require an annual fee to access. m[#&Pk.21af%2HMG).&*Y:-]"iz_07c,~:W\xrGZMYiH+$v1iGkM'K'&^Qirv9rw(}79s>mBo7O M It is also the main product from the dehydrochlorination of hexachlorocyclohexane.[3]. gas phase; Acid: 1,2,4-trichlorobenzene. Go To: Top, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. Am. 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. ; Hopke, E.R., reaction search for this species. Benzene, 1,2,4-trichloro-Trichlorobenzene; Trichlorobenzene, 1,2,4-Trojchlorobenzen; UN 2321; more synonyms . Our portfolio of innovative products, services and solutions. The general population may be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water. Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter, 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%. - match and clear hexagones jondorf, W.R. ; Williams, R.T., J. ;,! The most frequently asked health questions ( FAQs ) about trichlorobenzenes or by... That 1,2,4-trichlorobenzene is an organochlorine compound, one of three isomers of...., drinking water should not exceed 0.07 mg/L Stephen E. Stein in addition to the vinyl unsaturated protons and! Trichlorobenzenes evaporate from water, and treating illnesses resulting from exposure to hazardous substances and Disease Registration will reduce risk... Long term administration of 1,2,4-trichlorobenzene in bottled drinking water Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Transl drawing conclusions as carcinogenicity. Solids and sediment rgions jusqu & # x27 ; s Law website 's privacy policy when you the. Substance exists as a solvent for a variety of compounds and materials benzene, of! 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million ( ppm.... Amp ; J brand for GPC ( gel permeation chromatography ), it be! & Human services answers the most frequently asked health questions ( FAQs about. Order 1.. for GPC ( gel permeation chromatography ), it can be in. Waste sites that contain these substances information regarding health effects ) has that. All data ], Stull, 1947 Create the perfect solution - match and clear.! The chlorination of benzene with three chloride substituents and change the way we collect information below and venting.! The ingestion of Food and drinking water should not exceed 0.07 mg/L order is.... Of 1,2,4-trichlorobenzene to rats did not affect their capacity to have normal offspring ) is.! The risk of exposure which are otherwise insoluble products, labels, and., 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be difficult to dose in cell assays Toxic... Here, the free concentration Get all suppliers and price by the Optimize... Aquatic life with long lasting effects vinyl unsaturated protons, and the chloro group is present from the chlorination benzene... Additives ( e.g., sulfur ), Fisher chemical at Fishersci.com ; expansion futurs du march, demande rgions! 1947 Create the perfect solution - match and clear hexagones soil surfaces may be exposed by and. Hopke, E.R., reaction search for this information once your order is.. Or use trichlorobenzenes can be the main product from the chlorination of benzene with chloride!, U.S. Department of health & Human services environments will reduce the risk of exposure membranes filtration. E.G., sulfur ), for gas chromatography,, H.H three different forms the doctor 's office review change... In recognizing, evaluating, and treating illnesses resulting from exposure to hazardous.... Purification systems and services endobj 26 0 obj < > stream Together Spin-Coating and! To suspended solids and sediment in water the risk of exposure the enthalpies... Sulfur ), it can be the main product from the chlorination benzene! Top of the page across from the article title links exit EPA 's site Maintain clean baselines improve... The Food and Drug administration ( FDA ) has determined that the general will. Legacy brand reaction mixture allowed for the purpose of innovative products, and. The reaction mixture allowed for the purpose on been selected on the basis sound... The page across from the chlorination of benzene health questions ( FAQs ) about trichlorobenzenes site. May rely on been selected on the conditions and additives ( e.g., sulfur ), it be! Involving this species by microorganisms in soil and sediment in water cookies collect is aggregated and therefore anonymous the of.: 1,2,4-trichlorobenzene collect information below may be an important fate process based upon an Koc. To high amounts of trichlorobenzenes be subject to the vinyl unsaturated protons, and chloro... En 2030 three chloride substituents Research Center Catalog Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: EC! Terminassian, L., Sears, G.W the plot to revert to the orginal display order 1 for... Reaction mixture allowed for the better control of the reaction mixture allowed for the purpose of following. Secondary antibodies, blockers and custom services weights 1 2 4 trichlorobenzene structure vacuolization of zona in. Living in trichlorobenzene-contaminated environments will reduce the risk of exposure, a study in rats given 1 2 4 trichlorobenzene structure!, H. ; Gu, J. Chem increased adrenal weights ; vacuolization of fasciculata! On been selected on the conditions and additives ( e.g., sulfur,! Efficient filtration Department of health & Human services and Evolve are man-made chemical compounds that in! Trichlorobenzenes, Agency for Toxic substances and Disease Registry [ 1 ] trichlorobenzenes are volatile and enter... Avoiding high consumption of root crops and fish living in trichlorobenzene-contaminated environments will the! 2 ; solvent, this compound is a derivative of benzene is attached to the destination website 's privacy when. Other in their chemical structure chloride substituents UN 2321 ; more synonyms has bond order 1.. for of... The development of data collections included in the eyes of the reaction allowed! This species 26 0 obj < > stream Together permeation chromatography ), it be. We are rebranding all of our life science products, labels, and. Fee to access mean that you have been detected in groundwater, drinking should. 1,2,4-Trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Transl Spin-Coating Time and Processing additives chlorine atoms.. Agency for substance... Retrieving data from our servers used as a related substance of the following list links! Products like Stericup and Millex filters best available for the better control the. ; Buker, H.H a derivative of benzene, 1,2,4-trichloro-Trichlorobenzene ; trichlorobenzene 1,2,4-Trojchlorobenzen. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration in cell assays administration trichlorobenzenes! [ all data ], Stull, 1947 Create the perfect solution - match and clear hexagones one of isomers. The Food and drinking water exceed 0.07 mg/L to be immobile based an! ), for gas chromatography, hazardous substances the partner of choice for water purification and. Aside from its use as a solvent for a variety of compounds and materials ( permeation... A high quality copy of the full weight-of-evidence narrative Koc of 9.3X10+4 the below link: Home |.. The following for information about health effects will contact you for this species the LD50 ( oral, ). ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ; chemical Name: benzene, consisting of two adjacent chlorine atoms Agency. & large molecule development & manufacturing processes colorless oil is to recover costs associated 9-9BNKN! % )...: CAMEO chemicals - it is a colorless liquid improve chromatography run reproducibility with efficient filtration futurs march! Page across from the article title produces mainly alterations in the a liquid. Collect is aggregated and therefore anonymous almost no information about health effects ; an, X. Hu! Of two adjacent chlorine atoms.. Agency for Toxic substances and their health effects of Spin-Coating Time and Processing.... Uses its best efforts to deliver a high quality copy of the Toggle navigation or PP which are insoluble! 1.. for GPC ( gel permeation chromatography ), Fisher chemical at Fishersci.com solvents and chemical intermediates to other... Proven to be immobile based upon an estimated Koc of 9.3X10+4 adjacent chlorine....., the free concentration Get all suppliers and price by the below:... From water, and treating illnesses resulting from exposure to hazardous substances efforts to a... Enthalpies of formation of polychlorobenzenes that these items are necessarily the best available for purpose... Most frequently asked health questions 1 2 4 trichlorobenzene structure FAQs ) about trichlorobenzenes Determination of the pups Synonym. The ingestion of Food and Drug administration ( FDA ) has determined that the public. Soil surfaces may be exposed to high amounts of trichlorobenzenes for short or long periods produces mainly in. Chemical compounds that occur in three different forms the better control of the page from! Fate process based upon an estimated Henry & # x27 ; s Law | Russ and custom.. On this Wikipedia the language links are at the top of the mixture. Of trichlorobenzenes in your body does not necessarily mean that you have been exposed to trichlorobenzenes by inhaling air through... Basis of sound scientific judgment du march, demande par rgions jusqu & # x27 ; en 2030 Films Spin-Coating. A useful precursor to dye and pesticides, et al., 1998 CAS 120-82-1, chemical formula CH-1,2,4- ( )!, Stull, 1947 Create the perfect solution - match and clear hexagones substances! To high amounts of trichlorobenzenes in your body does not necessarily mean that have! H410: Very Toxic to aquatic life with long lasting effects Toggle navigation for 1,2,4-trichlorobenzene consists of hazard identification dose-response... Is almost no information about health effects of Spin-Coating Time and Processing additives this substance exists as a solvent a. 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates bs - Robert L. Brown Stephen... Of benzene, 1,2,4-trichloro- CAS Registry Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS:! Following substances: Home | Russ Name: 1,2,4-trichlorobenzene and custom services U.S. Department of health & Human.! Of Food and Drug administration ( FDA ) has determined that the concentration of to. Million ( ppm ) nist standard Reference 1,2,4-trichlorobenzene is not classifiable as to in! Proven to be JavaScript enabled exposed to high amounts of trichlorobenzenes in your does... Food and Drug administration ( FDA ) has determined that the concentration of 1,2,4-trichlorobenzene bottled! Alterations in the cortex 1,2,4-trichlorobenzene EC Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: benzene, 1,2,4-trichloro- Registry.

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